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Review
. 2015 Apr-Jun;63(2):87-93.

THE EXTRASKELETAL ACTIONS OF VITAMIN D--MYTHS AND FACTS

Amer Sebaaly, Falah Bachour, Wael Bayoud, Gemma Adib, Farid Bedran, Clea Daher, Ghassan Maalouf
  • PMID: 26164977
Review

THE EXTRASKELETAL ACTIONS OF VITAMIN D--MYTHS AND FACTS

Amer Sebaaly et al. J Med Liban. 2015 Apr-Jun.

Abstract

Vitamin D is well known for its effects on bone metabolism, calcium and phosphorus homeostasis. Recently, a worldwide focus has been made on the extraskeletal effects of this liposoluble vitamin. The New York Times even called it the "wonder drug". Vitamin D is a liposoluble vitamin and acts via an intracellular receptor. This article reviews the extra-skeletal effects of vitamin D focusing on cardiovascular effects, regulation of glucose, antitumoral properties, and effect on the immune system and the skeletal muscle and attempts to offer possible molecular explanations to these effects.

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