Sleep disorders and respiratory function in amyotrophic lateral sclerosis

Rebekah M Ahmed¹, Rowena E A Newcombe², Amanda J Piper³, Simon J Lewis⁴, Brendon J Yee³, Matthew C Kiernan⁵, Ron R Grunstein³

Affiliations

¹ Brain and Mind Research Institute and Department of Neurology Royal Prince Alfred Hospital, University of Sydney, Sydney, New South Wales, Australia. Electronic address: r.ahmed@neura.edu.au.
² NHMRC Centre for Integrated Research and Understanding of Sleep (CIRUS), Woolcock Institute of Medical Research and NeuroSleep NHMRC Centre for Research Excellence, Australia.
³ NHMRC Centre for Integrated Research and Understanding of Sleep (CIRUS), Woolcock Institute of Medical Research and NeuroSleep NHMRC Centre for Research Excellence, Australia; Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Sydney Local Health District, Australia.
⁴ Brain and Mind Research Institute and Department of Neurology Royal Prince Alfred Hospital, University of Sydney, Sydney, New South Wales, Australia; NHMRC Centre for Integrated Research and Understanding of Sleep (CIRUS), Woolcock Institute of Medical Research and NeuroSleep NHMRC Centre for Research Excellence, Australia.
⁵ Brain and Mind Research Institute and Department of Neurology Royal Prince Alfred Hospital, University of Sydney, Sydney, New South Wales, Australia.

PMID: 26166297
DOI: 10.1016/j.smrv.2015.05.007

Review

Sleep disorders and respiratory function in amyotrophic lateral sclerosis

Rebekah M Ahmed et al. Sleep Med Rev. 2016 Apr.

. 2016 Apr:26:33-42.

doi: 10.1016/j.smrv.2015.05.007. Epub 2015 Jun 3.

Authors

Rebekah M Ahmed¹, Rowena E A Newcombe², Amanda J Piper³, Simon J Lewis⁴, Brendon J Yee³, Matthew C Kiernan⁵, Ron R Grunstein³

Affiliations

¹ Brain and Mind Research Institute and Department of Neurology Royal Prince Alfred Hospital, University of Sydney, Sydney, New South Wales, Australia. Electronic address: r.ahmed@neura.edu.au.
² NHMRC Centre for Integrated Research and Understanding of Sleep (CIRUS), Woolcock Institute of Medical Research and NeuroSleep NHMRC Centre for Research Excellence, Australia.
³ NHMRC Centre for Integrated Research and Understanding of Sleep (CIRUS), Woolcock Institute of Medical Research and NeuroSleep NHMRC Centre for Research Excellence, Australia; Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Sydney Local Health District, Australia.
⁴ Brain and Mind Research Institute and Department of Neurology Royal Prince Alfred Hospital, University of Sydney, Sydney, New South Wales, Australia; NHMRC Centre for Integrated Research and Understanding of Sleep (CIRUS), Woolcock Institute of Medical Research and NeuroSleep NHMRC Centre for Research Excellence, Australia.
⁵ Brain and Mind Research Institute and Department of Neurology Royal Prince Alfred Hospital, University of Sydney, Sydney, New South Wales, Australia.

PMID: 26166297
DOI: 10.1016/j.smrv.2015.05.007

Abstract

Sleep disorders in amyotrophic lateral sclerosis (ALS) present a significant challenge to the management of patients. Issues include the maintenance of adequate ventilatory status through techniques such as non-invasive ventilation, which has the ability to modulate survival and improve patient quality of life. Here, a multidisciplinary approach to the management of these disorders is reviewed, from concepts about the underlying neurobiological basis, through to current management approaches and future directions for research.

Keywords: Amyotrophic lateral sclerosis; Respiratory; Sleep; Ventilation.

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Sleep disorders and respiratory function in amyotrophic lateral sclerosis

Affiliations

Sleep disorders and respiratory function in amyotrophic lateral sclerosis

Authors

Affiliations

Abstract

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Miscellaneous