Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Jun 25:8:307-12.
doi: 10.2147/CCID.S84117. eCollection 2015.

Correction of tear trough deformity with a cohesive polydensified matrix hyaluronic acid: a case series

Jürgen Huber-Vorländer  1 , Martin Kürten  1
Affiliations

Correction of tear trough deformity with a cohesive polydensified matrix hyaluronic acid: a case series

Jürgen Huber-Vorländer et al. Clin Cosmet Investig Dermatol. .

Abstract

The tear trough or infraorbital hollow is a challenging area to treat, and only a few fillers are suitable for this delicate area. We report on a European case series of six subjects with mild to severe tear troughs who received treatment with cohesive polydensified matrix (CPM(®)) technology hyaluronic acid gel (Belotero(®) Balance). The product was injected as small depots (up to ten small boli 0.2 mL maximum each per side) at the supraperiosteal level along or below the orbital rim. Follow-up visits took place at 1, 3, 6, and 9 months after injection for independent evaluation of the clinical effect using the Merz Aesthetics Scale™ for infraorbital hollows and the Global Aesthetic Improvement Scale. Adverse events were also recorded. Mean hollowness scores were considerably improved compared with baseline in all subjects. In all women, the improvements remained throughout the 9-month study, with none reverting to their baseline score. Subjects' satisfaction with treatment was very high throughout the study, and all women stated that they would repeat treatment with the same product. The CPM hyaluronic acid gel was well tolerated. CPM hyaluronic acid gel is a safe and effective treatment for the tear trough area.

Keywords: Belotero® Balance; cohesive polydensified matrix (CPM®); hyaluronic acid; infraor-bital hollow; tear trough.

PubMed Disclaimer

Figures

Figure 1
Figure 1
A 57-year-old female patient with a Merz Aesthetics Scale® score of 2 for infraorbital hollow at baseline (A) received supraperiosteal injections of 0.7 mL CPM® hyaluronic acid gel per side. (B) 3 months, (C) 6 months, and (D) 9 months after treatment.® Dr. Huber-Vorländer. Abbreviation: CPM, cohesive polydensified matrix.
Figure 2
Figure 2
A 53-year-old female patient with a Merz Aesthetics Scale® score of 1 for infraorbital hollow at baseline (A) received supraperiosteal injections of 0.95 mL CPM® hyaluronic acid gel per side. Complete correction remained throughout the observation period at (B) 3 months, (C) 6 months, and (D) 9 months after treatment.® Dr. Huber-Vorländer. Abbreviation: CPM, cohesive polydensified matrix.
Figure 3
Figure 3
A 57-year-old female patient with a Merz Aesthetics Scale® score of 2 for infraorbital hollow at baseline (A) received supraperiosteal injections of 0.7 mL CPM® hyaluronic acid gel per side. (B) 3 months, (C) 6 months, and (D) 9 months after treatment.® Dr. Huber-Vorländer. Abbreviation: CPM, cohesive polydensified matrix.
Figure 4
Figure 4
A 61-year-old female patient with a Merz Aesthetics Scale® score 3 for infraorbital hollow at baseline (A) received supraperiosteal injections of 0.6 mL CPM® hyaluronic acid gel per side. (B) 3 months, (C) 6 months, and (D) 9 months after treatment.® Dr. Huber-Vorländer. Abbreviation: CPM, cohesive polydensified matrix.
Figure 5
Figure 5
Subject satisfaction with treatment in six women treated with CPM® hyaluronic acid gel for tear troughs. Abbreviation: CPM, cohesive polydensified matrix.
See this image and copyright information in PMC

References

    1. The Merz Aesthetics Face Value beauty survey. Data on file. Frankfurt, Germany: Merz Pharmaceuticals GmbH; 2012.
    1. Hirmand H. Anatomy and nonsurgical correction of the tear trough deformity. Plast Reconstr Surg. 2010;125:699–708. - PubMed
    1. Goldberg RA, McCann JD, Fiaschetti D, Ben Simon GJ. What causes eyelid bags? Analysis of 114 consecutive patients. Plast Reconstr Surg. 2005;115:1395–1402. - PubMed
    1. Wong CH, Hsieh MK, Mendelson B. The tear trough ligament: anatomical basis for the tear trough deformity. Plast Reconstr Surg. 2012;129:1392–1402. - PubMed
    1. Funt DK. Avoiding malar edema during midface/cheek augmentation with dermal fillers. J Clin Aesthet Dermatol. 2011;4:32–36. - PMC - PubMed

LinkOut - more resources