Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015:72:59-71.
doi: 10.1007/978-94-017-9918-8_4.

Why and How Does Pressure Unfold Proteins?

Catherine A Royer  1
Affiliations
Review

Why and How Does Pressure Unfold Proteins?

Catherine A Royer. Subcell Biochem. 2015.

Abstract

This year, 2014, marks the 100th anniversary of the first publication reporting the denaturation of proteins by high hydrostatic pressure (Bridgman 1914). Since that time a large and recently increasing number of studies of pressure effects on protein stability have been published, yet the mechanism for the action of pressure on proteins remains subject to considerable debate. This review will present an overview from this author's perspective of where this debate stands today.

PubMed Disclaimer

LinkOut - more resources