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. 1989 Nov-Dec;83(6):787-90.
doi: 10.1016/0035-9203(89)90329-5.

Experimental production of new zymodemes of Entamoeba histolytica supports the hypothesis of genetic exchange

D Blanc  1 , R Nicholls, P G Sargeaunt
Affiliations

Experimental production of new zymodemes of Entamoeba histolytica supports the hypothesis of genetic exchange

D Blanc et al. Trans R Soc Trop Med Hyg. 1989 Nov-Dec.

Abstract

By mixing in culture zymodemes of Entamoeba histolytica, clones showing a different pattern from the 2 parents have been obtained on 3 occasions. Two new zymodemes (XI alpha- and XXI) have thus been produced, which belong to the third generation of a family of E. histolytica zymodemes apparently obtained by genetic exchange. A hypothesis for the molecular basis of those exchanges is discussed. We report also the observation of probable mutation.

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