The Feasibility of Extracorporeal Membrane Oxygenation in the Variant Airway Problems
- PMID: 26179424
- PMCID: PMC4905028
- DOI: 10.5761/atcs.oa.15-00073
The Feasibility of Extracorporeal Membrane Oxygenation in the Variant Airway Problems
Abstract
Introduction: Extracorporeal membrane oxygenation (ECMO) is widely used to treat respiratory distress during cardiac or respiratory arrest; moreover, its use is being extended to a wide variety of clinical fields. In this study we assess the utility of ECMO in the management of airway obstruction.
Patients and methods: 15 patients underwent ECMO for airway obstruction. We retrospectively analyzed and evaluated the feasibility of ECMO in the treatment of airway problems.
Results: Seven patients received ECMO to facilitate respiration and promote stability during trachea surgery. In six cases ECMO ceased immediately following the operation; in the remaining case ECMO cessation was delayed due to post-operative ARDS. In three cases emergency ECMO was used in response to respiratory arrest; two patients died. In five cases ECMO was emergently inserted to prevent death, following airway blockade by massive hemoptysis. One patient was not discharged from the intensive care unit. Another patient was transferred to a general ward but died from other causes.
Conclusion: ECMO is useful during anesthesia in patients at high risk of airway blockade, for example due to endobronchial bleeding, and during complex thoracic surgery. ECMO confers a safer environment during airway surgery, and its complication rate is acceptable.
Figures

Similar articles
-
Use of venovenous extracorporeal membrane oxygenation in central airway obstruction to facilitate interventions leading to definitive airway security.J Crit Care. 2013 Oct;28(5):669-74. doi: 10.1016/j.jcrc.2013.05.020. Epub 2013 Jul 8. J Crit Care. 2013. PMID: 23845793
-
[Experiences with venovenous extracorporeal membrane oxygenation (ECMO) support for thoracic surgery in Hungary. Retrospective clinical study].Orv Hetil. 2019 Oct;160(42):1655-1662. doi: 10.1556/650.2019.31530. Orv Hetil. 2019. PMID: 31608689 Hungarian.
-
National review of use of extracorporeal membrane oxygenation as respiratory support in thoracic surgery excluding lung transplantation.Eur J Cardiothorac Surg. 2015 Jan;47(1):87-94. doi: 10.1093/ejcts/ezu127. Epub 2014 Mar 21. Eur J Cardiothorac Surg. 2015. PMID: 24659317
-
Extracorporeal membrane oxygenation as life-saving bridge for patients with airway obstruction caused by neck and chest tumors to salvage procedure: an in-depth review.Int J Surg. 2025 Jan 1;111(1):1090-1100. doi: 10.1097/JS9.0000000000002008. Int J Surg. 2025. PMID: 40053807 Free PMC article. Review.
-
The use of extracorporeal membrane oxygenation in the anticipated difficult airway: a case report and systematic review.Can J Anaesth. 2018 Jun;65(6):685-697. doi: 10.1007/s12630-018-1099-x. Epub 2018 Mar 1. Can J Anaesth. 2018. PMID: 29497994 English.
Cited by
-
ECMO-assisted bronchoscopic therapy for severe tracheal stenosis: a case report and literature review.BMC Pulm Med. 2025 Mar 31;25(1):144. doi: 10.1186/s12890-025-03612-1. BMC Pulm Med. 2025. PMID: 40165148 Free PMC article. Review.
-
Extracorporeal support in airway surgery.J Thorac Dis. 2017 Jul;9(7):2108-2117. doi: 10.21037/jtd.2017.06.17. J Thorac Dis. 2017. PMID: 28840012 Free PMC article. Review.
-
Intraoperative airway management for patients with tracheal tumors: A case series of 37 patients.Thorac Cancer. 2021 Nov;12(22):3046-3052. doi: 10.1111/1759-7714.14181. Epub 2021 Oct 9. Thorac Cancer. 2021. PMID: 34626082 Free PMC article.
-
Innovative Approaches in Tracheal Resection and Anastomosis Surgery: Integrating Extracorporeal Membrane Oxygenation for Enhanced Safety.Yonsei Med J. 2025 May;66(5):289-294. doi: 10.3349/ymj.2024.0236. Yonsei Med J. 2025. PMID: 40288900 Free PMC article.
-
The role of ECMO support in airway procedures.BJA Educ. 2023 Jul;23(7):248-255. doi: 10.1016/j.bjae.2023.03.007. Epub 2023 May 9. BJA Educ. 2023. PMID: 37389276 Free PMC article. Review. No abstract available.
References
-
- Granholm T, Farmer DL. The surgical airway. Respir Care Clin N Am 2001; 7: 13-23. - PubMed
-
- Johnson NJ, Acker M, Hsu CH, et al. Extracorporeal life support as rescue strategy for out-of-hospital and emergency department cardiac arrest. Resuscitation 2014; 85: 1527-32. - PubMed
-
- Onozawa H, Tanaka T, Takinami M, et al. Anesthetic management using extracorporeal circulation of a patient with severe tracheal stenosis by thyroid cancer. Masui 1999; 48: 658-61. - PubMed
-
- Chen A. ECMO-assisted rigid bronchoscopy for tracheal obstruction. J Bronchology Interv Pulmonol 2009; 16: 296-7. - PubMed
-
- Kaneko T, Itani M, Komasawa N, et al. Anesthesia for tracheal metal stent management utilizing venovenous extracorporeal life support. Masui 2012; 61: 1269-72. - PubMed
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical