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Review
. 2015 Jul-Aug;25(4):517-27.
doi: 10.1111/jon.12272.

Imaging in Endovascular Stroke Trials

Affiliations
Review

Imaging in Endovascular Stroke Trials

Konark Malhotra et al. J Neuroimaging. 2015 Jul-Aug.

Abstract

Ischemic stroke remains a leading cause of death and disability worldwide. Various endovascular trials have addressed clinical outcomes without elucidating the impact of imaging studies in patient selection. The success of recent endovascular trials was bolstered by the use of advanced imaging techniques for optimal selection of reperfusion candidates. This seminal juncture in the history of stroke trials warrants further consideration on the use of imaging to guide future refinements in the treatment of acute stroke. In this article, we systematically review the imaging methodology and key facets used in all published endovascular stroke trials to date, discuss the success of recent trials using latest advanced imaging techniques and focus on the importance of imaging studies for future patient selection.

Keywords: Neuroimaging; clinical trials; endovascular therapy; stroke.

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References

    1. Mozaffarian D, Benjamin EJ, Go AS, et al. Heart disease and stroke statistics--2015 update: a report from the American Heart Association. Circulation. 2015;131:17. - PubMed
    1. Hacke W, Furlan AJ, Al-Rawi Y, et al. Intravenous desmoteplase in patients with acute ischaemic stroke selected by MRI perfusion-diffusion weighted imaging or perfusion CT (DIAS-2): a prospective, randomised, double-blind, placebo-controlled study. Lancet Neurol. 2009;8:141–150. - PMC - PubMed
    1. Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med. 1995;333:1581–1587. - PubMed
    1. Cocho D, Belvis R, Marti-Fabregas J, et al. Reasons for exclusion from thrombolytic therapy following acute ischemic stroke. Neurology. 2005;64:719–720. - PubMed
    1. DeLaPaz RL, Wippold FJ, 2nd, Cornelius RS, et al. ACR Appropriateness Criteria(R) on cerebrovascular disease. J Am Coll Radiol. 2011;8:532–538. - PubMed

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