Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2015 Jul 8;3(6):e434.
doi: 10.1097/GOX.0000000000000412. eCollection 2015 Jun.

Post Reconstruction Breast Pyoderma Gangrenosum: Early Recognition and Prosthesis Salvage

Affiliations
Case Reports

Post Reconstruction Breast Pyoderma Gangrenosum: Early Recognition and Prosthesis Salvage

Bryan Cicuto et al. Plast Reconstr Surg Glob Open. .

Abstract

We report 3 cases of breast pyoderma gangrenosum in patients undergoing total mastectomy with immediate reconstruction. All three received systemic corticosteroid treatment, resulting in resolution of symptoms. As experience grew, early diagnosis in the third patient helped prosthesis salvage and timely return to the original course of reconstruction. This represents the first report of prosthesis salvage from post breast reconstruction pyoderma gangrenosum, and it demonstrates that implant removal is not always necessary during management of this rare condition.

PubMed Disclaimer

Conflict of interest statement

Disclosure: The authors have no financial interest to declare in relation to the content of this article. The Article Processing Charge was paid for by the authors.

Figures

Fig. 1.
Fig. 1.
A diagnosis of postsurgical pyoderma gangrenosum should be considered in cases of appearance of dermal yellow pustules with ulcerations that do not respond to antibiotic therapy at postoperative days 3–5.
Fig. 2.
Fig. 2.
Ulcerations seen on POD 10. On exploration, suture line skin edge necrosis was resected along with the surrounding ulcerative dermal tissue. There was no purulent drainage, fat necrosis, or fluid collection identified. Copious irrigation with antibiotic solution preceded partial tissue expander deflation to facilitate skin edge reapproximation, leaving the original tissue expander and Jackson-Pratt drain in place.
Fig. 3.
Fig. 3.
A–C, Histology of progressively higher powers of the dermal ulcerative specimen was consistent with the clinical diagnosis of pyoderma gangrenosum.

References

    1. Duval A, Boissel N, Servant JM, et al. Pyoderma gangrenosum of the breast: a diagnosis not to be missed. J Plast Reconstr Aesthet Surg. 2011;64:e17–e20. - PubMed
    1. Segaran A, Mohammad M, Sterling JC, et al. Pyoderma gangrenosum arising in a breast reduction scar: seven years post-procedure. J Plast Reconstr Aesthet Surg. 2013;66:e370–e372. - PubMed
    1. Wallach D, Vignon-Pennamen MD. From acute febrile neutrophilic dermatosis to neutrophilic disease: forty years of clinical research. J Am Acad Dermatol. 2006;55:1066–1071. - PubMed
    1. MacKenzie D, Moiemen N, Frame JD. Pyoderma gangrenosum following breast reconstruction. Br J Plast Surg. 2000;53:441–443. - PubMed
    1. Bonamigo RR, Behar PR, Beller C, et al. Pyoderma gangrenosum after silicone prosthesis implant in the breasts and facial plastic surgery. Int J Dermatol. 2008;47:289–291. - PubMed

Publication types