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. 2016;30(3):311-5.
doi: 10.1080/14786419.2015.1057730. Epub 2015 Jul 16.

New flavonoid and pentacyclic triterpene from Sesamum indicum leaves

Nguyen Tien Dat  1 , Nguyen Hai Dang  1 , Le Nguyen Thanh  1
Affiliations

New flavonoid and pentacyclic triterpene from Sesamum indicum leaves

Nguyen Tien Dat et al. Nat Prod Res. 2016.

Abstract

Two new and one known compounds were isolated from the methanol extract of Sesamum indicum leaves. By means of spectroscopic methods, their structures were elucidated and identified to be 3-epibartogenic acid (1), kaempferol 3-O-[2-O-(trans-p-coumaroyl)-3-O-α-L-rhamnopyranosyl]-β-D-glucopyranoside (2) and epigallocatechin (3). Compound 1 and 3 strongly inhibited α-amylase with the IC50 values of 146.7 and 303.9 μM, respectively, in comparison with acarbose (IC50 124.0 μM).

Keywords: Pedaliaceae, 3-epibartogenic acid; Sesamum indicum; α-amylase.

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