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Case Reports
. 2015 Jan-Mar;27(1):228-31.

PYREXIA-INDUCED BRUGADA PHENOCOPY

  • PMID: 26182783
Case Reports

PYREXIA-INDUCED BRUGADA PHENOCOPY

Nauman Khalid et al. J Ayub Med Coll Abbottabad. 2015 Jan-Mar.

Abstract

Brugada syndrome (BS) is characterized by a typical electrocardiographic (ECG) pattern in the right precordial leads and a predisposition to develop ventricular arrhythmias. Mutations in a subunit of cardiac sodium channel (SCN5A) have been linked to BS. Experimental studies in the literature suggest that this dysfunction of the mutated channel can be temperature sensitive. Several antiarrhythmics have been used in the management of BS but Implantable Cardioverter Defibrillators (ICD) remains the only effective treatment. We herewith present the case report of a 62-year-old man who developed a type-2 Brugada ECG phenotype in a febrile state with complete resolution once the fever subsided.

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