Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2015 Nov;29(11):1446-52.
doi: 10.1038/eye.2015.133. Epub 2015 Jul 17.

Comparison of photoreceptor outer segment length in diabetic and idiopathic epiretinal membranes

K Yüksel  1 , Y Karaküçük  2 , A Özkaya  1 , G Pekel  3 , Ö Baz  1 , C Alagöz  1 , A T Yazıcı  1
Affiliations
Comparative Study

Comparison of photoreceptor outer segment length in diabetic and idiopathic epiretinal membranes

K Yüksel et al. Eye (Lond). 2015 Nov.

Abstract

Purpose: Idiopathic and diabetic epiretinal membranes (ERMs) differ significantly in terms of macular morphology. Our aim was to compare the photoreceptor outer segment (PROS) length in diabetic and idiopathic ERMs before and after surgery.

Methods: Fifty-two eyes of 50 patients who underwent pars plana vitrectomy (PPV) due to idiopathic and diabetic ERMs were included in this retrospective case series. All of the patients underwent ERM and internal limiting membrane (ILM) removal. The patients had been followed up 6 months postoperatively. Spectral-domain optical coherence tomography (OCT) was used to measure the PROS length, overall PR length and central foveal thickness (CFT).

Results: The PROS length, overall PR length, and CFT were statistically significantly lower at all the postoperative visits when compared to preoperative values in both the idiopathic and diabetic ERM groups (P<0.001). The amount of decrease in PROS and overall PR length were similar in both groups after surgery (P>0.05). There was no relation between amount of PROS length change and visual acuity gain in both groups (P>0.05).

Conclusions: Postoperative change of PROS length was similar in idiopathic and diabetic ERMs. PROS length change may not be an indicator of postoperative visual acuity.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Spectral domain OCT images that show the preoperative (b) and postoperative (d) measurements of PROS and overall PR length, as well as the posterior segment photos (a and c).
Figure 2
Figure 2
Scatter plot graphics that show the correlation of visual acuity gain and PROS length difference between the preoperative and last visits in diabetic and idiopathic ERM groups.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Joshi M, Agrawal S, Christoforidis JB. Inflammatory mechanisms of idiopathic epiretinal membrane formation. Mediators Inflamm 2013; 2013: 192582. - PMC - PubMed
    1. Hiscott PS, Grierson I, McLeod D. Natural history of fibrocellular epiretinal membranes: a quantitative, autoradiographic, and immunohistochemical study. Br J Ophthalmol 1985; 69: 810–823. - PMC - PubMed
    1. Harada C, Mitamura Y, Harada T. The role of cytokines and trophic factors in epiretinal membranes: involvement of signal transduction in glial cells. Prog Retin Eye Res 2006; 25: 149–164. - PubMed
    1. Appiah AP, Hirose T. Secondary causes of premacular fibrosis. Ophthalmology 1989; 96: 389–392. - PubMed
    1. Srinivasan VJ, Wojtkowski M, Witkin AJ, Duker JS, Ko TH, Carvalho M et al. High-definition and 3-dimensional imaging of macular pathologies with high speed ultrahigh-resolution optical coherence tomography. Ophthalmology 2006; 113: 2054.e1–2054.14. - PMC - PubMed

Publication types