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Review
. 2015 Aug;73(2):181-90, quiz 191-2.
doi: 10.1016/j.jaad.2015.04.014.

Melanoma in situ: Part I. Epidemiology, screening, and clinical features

H William Higgins 2nd  1 , Kachiu C Lee  2 , Anjela Galan  3 , David J Leffell  4
Affiliations
Review

Melanoma in situ: Part I. Epidemiology, screening, and clinical features

H William Higgins 2nd et al. J Am Acad Dermatol. 2015 Aug.

Abstract

The incidence of melanoma has steadily increased over the past 3 decades, with melanoma in situ comprising a disproportionately high percentage of the rising incidence. Our understanding of melanoma in situ has been shaped by epidemiologic and clinical studies. Central to a review of melanoma in situ is a focus on its epidemiology, pathology, biologic behavior, treatment, and clinical outcome, which may differ significantly from that of malignant melanoma. Part I of this continuing medical education article reviews the epidemiology, risk factors, and clinical features of melanoma in situ; part II covers the histopathology, treatment options, and clinical management.

Keywords: lentigo maligna; melanoma; melanoma in situ.

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