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Editorial
. 2015 Aug;12(4):329-31.
doi: 10.1586/14789450.2015.1064771.

Proteomic methods for biomarker discovery and validation. Are we there yet?

Yetrib Hathout  1
Affiliations
Editorial

Proteomic methods for biomarker discovery and validation. Are we there yet?

Yetrib Hathout. Expert Rev Proteomics. 2015 Aug.

Abstract

Noninvasive molecular biomarkers are becoming attractive tools to monitor disease progression, aid drug development programs and use as surrogate outcome measures in clinical trials. Cutting edge proteomic methods to assay biomarkers in body fluids have been developed in the past few years, but transitioning them to clinical practice has been slow and depends on the qualification of both the method and the biomarker.

Keywords: SomaScan; antibody bead arrays; biomarkers; biomarkers validation; proteomics; targeted mass spectrometry.

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