[Studies on the chemical constituents of Aquilaria sinensis(Lour.) Gilg. IV. Isolation and characterization of 2-(2-phenylethyl)chromone derivatives]

Abstract

Six chromone derivatives were isolated from the ether soluble fraction of the alcoholic extract of Aquilaria sinensis(Lour.) Gilg. (Thymeleaceae) by silica gel chromatography. On the basis of spectrometric data (UV, IR, 1HNMR and 13CNMR as well as MS) and chemical synthesis one of them was found to be a new chromone, 6-hydroxy-2-[2-(4'-methoxylphenyl)ethyl]chromone(VI) and the other five known chromones are 2-(2-phenylethyl)chromone(I), 6-methoxy-2-(2-phenylethyl)chromone (II), 6.7-dimethoxy-2-(2-phenylethyl)chromone(III), 6-methoxy-2[2-(3'-methoxyphenyl)ethyl]chromone(IV) and 6-hydroxy-2-(2-phenylethyl) chromone(V). These compounds were obtained for the first time from this plant.