Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989 Dec;55(12):3140-2.
doi: 10.1128/aem.55.12.3140-3142.1989.

Aromatic hydroxylation and sulfation of 5-hydroxyflavone by Streptomyces fulvissimus

A R Ibrahim  1 , Y J Abul-Hajj
Affiliations

Aromatic hydroxylation and sulfation of 5-hydroxyflavone by Streptomyces fulvissimus

A R Ibrahim et al. Appl Environ Microbiol. 1989 Dec.

Abstract

The conversion of 5-hydroxyflavone by various microorganisms was studied. Among them, Streptomyces fulvissimus was the sole microbe which produced a new polar metabolite from 5-hydroxyflavone in addition to 5,4-dihydoxy- and 5,3,4-trihydroxyflavone. The structure of this polar metabolite was determined to be 5,4-dihydroxyflavone-4-sulfate on the basis of mass, infrared, and nuclear magnetic resonance spectroscopies. These results demonstrate that S. fulvissimus catalyzes sulfation at the 4 position of 4,5-dihydroxyflavone.

PubMed Disclaimer

References

    1. Science. 1977 Aug 5;197(4303):577-8 - PubMed
    1. Endocrinology. 1978 Nov;103(5):1860-7 - PubMed
    1. Adv Food Res. 1981;27:149-242 - PubMed
    1. Appl Environ Microbiol. 1982 May;43(5):1070-5 - PubMed
    1. Cancer Res. 1982 Dec;42(12):4875-917 - PubMed

LinkOut - more resources