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. 2015 Jul 21;12(7):e1001855.
doi: 10.1371/journal.pmed.1001855. eCollection 2015 Jul.

Individual Participant Data (IPD) Meta-analyses of Randomised Controlled Trials: Guidance on Their Use

Jayne F Tierney  1 , Claire Vale  1 , Richard Riley  2 , Catrin Tudur Smith  3 , Lesley Stewart  4 , Mike Clarke  5 , Maroeska Rovers  6
Affiliations

Individual Participant Data (IPD) Meta-analyses of Randomised Controlled Trials: Guidance on Their Use

Jayne F Tierney et al. PLoS Med. .

Abstract

Jayne Tierney and colleagues offer guidance on how to spot a well-designed and well-conducted individual participant data meta-analysis.

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Conflict of interest statement

We have read the journal's policy and have the following potential conflicts. JFT, LS, MC and MR are co-convenors of the Cochrane IPD Methods Group. All authors have been involved in the conduct and publication of IPD meta-analyses, related methodological research and guidance on the IPD approach to systematic review, and receive funding for these activities.

References

    1. Higgins JPT, Green SJ, editors. Cochrane Handbook for Systematic Reviews of Interventions. Chichester: John Wiley & Sons Ltd; 2008.
    1. Sterne JAC, Egger M, Moher D, on behalf of the Cochrane Bias Methods Group. Addressing reporting biases In: Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions. Chichester: Wiley & Sons Ltd; 2008. p. 297–333.
    1. Stewart LA, Clarke MJ, on behalf of the Cochrane Working Party Group on Meta-analysis using Individual Patient Data. Practical methodology of meta-analyses (overviews) using updated individual patient data. Stat Med. 1995;14:2057–79. - PubMed
    1. Stewart LA, Tierney JF. To IPD or Not to IPD? Advantages and disadvantages of systematic reviews using individual patient data. Eval Health Prof. 2002;25(1):76–97. - PubMed
    1. Stewart LA, Tierney JF, Clarke M, on behalf of the Cochrane Individual Patient Data Meta-analysis Methods Group. Reviews of individual patient data In: Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions. Chichester: Wiley & Sons Ltd; 2008. p. 547–58.

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