Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Practice Guideline
. 2015 Apr;37(3):e162-9.
doi: 10.1097/MPH.0000000000000307.

Guidelines for the Standard Monitoring of Patients With Thalassemia: Report of the Thalassemia Longitudinal Cohort

Venée N Tubman  1 , Ellen B Fung, Maria Vogiatzi, Alexis A Thompson, Zora R Rogers, Ellis J Neufeld, Janet L Kwiatkowski; Thalassemia Clinical Research Network
Collaborators, Affiliations
Practice Guideline

Guidelines for the Standard Monitoring of Patients With Thalassemia: Report of the Thalassemia Longitudinal Cohort

Venée N Tubman et al. J Pediatr Hematol Oncol. 2015 Apr.

Abstract

Chronic transfusion therapy has played a central role in extending life expectancy for patients with hemoglobinopathies such as thalassemia. However, this life-saving therapy is associated with numerous complications that now comprise the bulk of management considerations for patients with thalassemia. This review reports on the experience of the Thalassemia Longitudinal Cohort and reviews available literature to establish guidelines for the management of patients with thalassemia.

PubMed Disclaimer

References

    1. Weatherall DJ, Williams TN, Allen SJ, O'Donnell A. The population genetics and dynamics of the thalassemias. Hematol Oncol Clin N Am. 2010;24:1021–1031. - PubMed
    1. Borgna-Pignatti C, Rugolotto S, De Stefano P, et al. Survival and complications in patients with thalassemia major treated with transfusion and deferoxmine. Haematologia. 2004;89:1187–1193. - PubMed
    1. Kwiatkowski JL, Kim H-Y, Thompson AA, et al. Chelation use and iron burden in North American and British thalassemia patients: a report from the Thalassemia Longitudinal Cohort. Blood. 2012;119:2746–2753. - PMC - PubMed
    1. Sirchia G, Zanella A, Parravicini A, et al. Red cell alloantibodies in thalassemia major. Results of an Italian cooperative study. Transfusion. 1985;25:110–112. - PubMed
    1. Thompson AA, Cunningham MJ, Singer ST, et al. Red cell alloimmunization in a diverse population of transfused patients with thalassaemia. Br J Haematol. 2011;153:121–128. - PMC - PubMed

Publication types