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Editorial
. 2015 Jun 30;6(18):15706-7.
doi: 10.18632/oncotarget.4480.

IP3 3-kinase B prevents bone marrow failure

Stephanie Rigaud  1 , Karsten Sauer  1   2
Affiliations
Editorial

IP3 3-kinase B prevents bone marrow failure

Stephanie Rigaud et al. Oncotarget. .
No abstract available

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Figures

Figure 1
Figure 1
Symmetric signaling by PI3K and Itpkb through the antagonistic second messengers PIP3 and IP4 restricts signaling by Akt and downstream mTORC1 in HSC into a window that ensures self-renewal, quiescence and longevity but prevents activation, differentiation and eventual depletion [2].
See this image and copyright information in PMC

References

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    1. Sauer K, et al. Nat Rev Immunol. 2010;10:257–271. - PMC - PubMed

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