Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2015 Aug;64(8):2720-2.
doi: 10.2337/db15-0532.

Causal or Noncausal Relationship of Uric Acid With Diabetes

Affiliations
Comment

Causal or Noncausal Relationship of Uric Acid With Diabetes

Richard J Johnson et al. Diabetes. 2015 Aug.
No abstract available

PubMed Disclaimer

Comment on

  • A Mendelian Randomization Study of Circulating Uric Acid and Type 2 Diabetes.
    Sluijs I, Holmes MV, van der Schouw YT, Beulens JW, Asselbergs FW, Huerta JM, Palmer TM, Arriola L, Balkau B, Barricarte A, Boeing H, Clavel-Chapelon F, Fagherazzi G, Franks PW, Gavrila D, Kaaks R, Khaw KT, Kühn T, Molina-Montes E, Mortensen LM, Nilsson PM, Overvad K, Palli D, Panico S, Quirós JR, Rolandsson O, Sacerdote C, Sala N, Schmidt JA, Scott RA, Sieri S, Slimani N, Spijkerman AM, Tjonneland A, Travis RC, Tumino R, van der A DL, Sharp SJ, Forouhi NG, Langenberg C, Riboli E, Wareham NJ; InterAct Consortium. Sluijs I, et al. Diabetes. 2015 Aug;64(8):3028-36. doi: 10.2337/db14-0742. Epub 2015 Apr 27. Diabetes. 2015. PMID: 25918230 Free PMC article.

References

    1. Kratzer JT, Lanaspa MA, Murphy MN, et al. . Evolutionary history and metabolic insights of ancient mammalian uricases. Proc Natl Acad Sci U S A 2014;111:3763–3768 - PMC - PubMed
    1. Ames BN, Cathcart R, Schwiers E, Hochstein P. Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis. Proc Natl Acad Sci U S A 1981;78:6858–6862 - PMC - PubMed
    1. Johnson RJ, Andrews P. The fat gene: a genetic mutation in prehistoric apes may underlie today's pandemic of obesity and diabetes. Sci Am. In press
    1. Ishimoto T, Lanaspa MA, Le MT, et al. . Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice. Proc Natl Acad Sci U S A 2012;109:4320–4325 - PMC - PubMed
    1. Lanaspa MA, Cicerchi C, Garcia G, et al. . Counteracting roles of AMP deaminase and AMP kinase in the development of fatty liver. PLoS One 2012;7:e48801. - PMC - PubMed