DNMT1 and Cancer: An Electrifying Link
- PMID: 26207295
- DOI: 10.1016/j.chembiol.2015.07.004
DNMT1 and Cancer: An Electrifying Link
Abstract
Aberrant epigenetic methylation is linked to the onset and progression of cancer. In this issue of Chemistry & Biology, Furst and Barton (2015) describe a sensitive electrochemical assay that can detect hyperactive epigenetic methylation in tumor tissue.
Copyright © 2015 Elsevier Ltd. All rights reserved.
Comment on
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DNA Electrochemistry Shows DNMT1 Methyltransferase Hyperactivity in Colorectal Tumors.Chem Biol. 2015 Jul 23;22(7):938-45. doi: 10.1016/j.chembiol.2015.05.019. Epub 2015 Jun 25. Chem Biol. 2015. PMID: 26120002 Free PMC article.
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