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Case Reports
. 2015 Aug:69:48-51.
doi: 10.1016/j.jcv.2015.05.019. Epub 2015 May 29.

Persistent viremia and urine shedding of tick-borne encephalitis virus in an infected immunosuppressed patient from a new epidemic cluster in North-Eastern Italy

Ilaria Caracciolo  1 , Matteo Bassetti  2 , Giorgio Paladini  3 , Roberto Luzzati  4 , Daniela Santon  1 , Maria Merelli  2 , Giovanni De Sabbata  3 , Tea Carletti  5 , Alessandro Marcello  6 , Pierlanfranco D'Agaro  7
Affiliations
Case Reports

Persistent viremia and urine shedding of tick-borne encephalitis virus in an infected immunosuppressed patient from a new epidemic cluster in North-Eastern Italy

Ilaria Caracciolo et al. J Clin Virol. 2015 Aug.

Abstract

A persistent tick-borne encephalitis virus infection in an immune-suppressed patient is presented. Such an unusual clinical case offers the unique chance of detecting persistent viremia associated to the erythrocyte fraction and shedding of the virus in the urine for more than six weeks. The infection occurred in a new area of the Friuli Venezia-Giulia region (North Eastern Italy) where two additional cases are also being reported.

Keywords: Friuli-Venezia Giulia region; Immuno-compromized host; Italy; Persistent infection; Real-time PCR; Sequencing; TBEV; Tick-borne encephalitis; Trieste; Virus isolation.

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