. 2015 Dec:19:86-9.

doi: 10.1016/j.eatbeh.2015.07.002. Epub 2015 Jul 18.

Metabolic characteristics of youth with loss of control eating

Affiliations

¹ Section on Growth and Obesity, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS, Bethesda, MD 20892-1103, USA; Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA.
² Section on Growth and Obesity, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS, Bethesda, MD 20892-1103, USA; Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
³ Section on Growth and Obesity, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS, Bethesda, MD 20892-1103, USA; Colorado State University, Fort Collins, CO 80523, USA.
⁴ Section on Growth and Obesity, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS, Bethesda, MD 20892-1103, USA.
⁵ Section on Growth and Obesity, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS, Bethesda, MD 20892-1103, USA; Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, USA.
⁶ Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, USA; Division of Nutrition Research Coordination, NIH, USA.
⁷ Section on Growth and Obesity, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS, Bethesda, MD 20892-1103, USA. Electronic address: jy15i@nih.gov.

PMID: 26210388
PMCID: PMC4644474
DOI: 10.1016/j.eatbeh.2015.07.002

Metabolic characteristics of youth with loss of control eating

Rachel M Radin et al. Eat Behav. 2015 Dec.

. 2015 Dec:19:86-9.

doi: 10.1016/j.eatbeh.2015.07.002. Epub 2015 Jul 18.

Affiliations

¹ Section on Growth and Obesity, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS, Bethesda, MD 20892-1103, USA; Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA.
² Section on Growth and Obesity, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS, Bethesda, MD 20892-1103, USA; Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
³ Section on Growth and Obesity, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS, Bethesda, MD 20892-1103, USA; Colorado State University, Fort Collins, CO 80523, USA.
⁴ Section on Growth and Obesity, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS, Bethesda, MD 20892-1103, USA.
⁵ Section on Growth and Obesity, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS, Bethesda, MD 20892-1103, USA; Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, USA.
⁶ Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, USA; Division of Nutrition Research Coordination, NIH, USA.
⁷ Section on Growth and Obesity, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), DHHS, Bethesda, MD 20892-1103, USA. Electronic address: jy15i@nih.gov.

PMID: 26210388
PMCID: PMC4644474
DOI: 10.1016/j.eatbeh.2015.07.002

Abstract

Purpose: Preliminary data in adults suggest that binge eating is associated with greater prevalence of metabolic syndrome (MetS) components. However, there are limited data in youth, and little is known of the role of binge episode size in these relationships.

Methods: We examined the relationship between loss of control eating and metabolic characteristics in a convenience sample of 329 treatment-seeking and non-treatment-seeking adolescent boys and girls. The sample was enriched by design with adolescents who were overweight or obese and with individuals who reported episodes of loss of control over their eating (either objectively large binge episodes, OBEs or subjectively large binge episodes, SBEs, in the past month), as assessed by clinical interview. MetS components (blood pressure, lipids, glucose, and waist circumference) were the primary variables of interest.

Results: 46% of the cohort reported loss of control eating; among those, 53% reported SBEs only and 47% reported OBEs. Youth with loss of control eating had higher systolic blood pressure (p=.001) and higher low-density lipoprotein cholesterol (LDL-c) (p=.002) compared to those without loss of control eating, in analyses adjusted for intervention-seeking status, fat mass and sociodemographic characteristics. Youth reporting OBEs had higher LDL-c (p=.013) compared to those reporting only SBEs.

Conclusions: Adolescents reporting loss of control episodes had greater dysfunction in some components of the MetS compared to youth without loss of control; episode size may contribute to metabolic dysfunction.

Trial registration: ClinicalTrials.gov NCT00001195 NCT00001522 NCT00001723 NCT00263536 NCT00631644 NCT00680979 NCT01425905.

Keywords: Adolescence; Binge eating; Loss of control eating; Metabolic dysfunction.

Published by Elsevier Ltd.

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Conflict of interest statement

Conflict of Interest:

All authors declare that they have no potential biomedical conflicts of interest, financial or otherwise, relevant to this article (Rachel M. Radin, Marian Tanofsky-Kraff, Lauren B. Shomaker, Nichole R. Kelly, Courtney K. Pickworth, Lisa M. Shank, Anne M. Altschul, Sheila M. Brady, Andrew P. Demidowich, Suzan Z. Yanovski, Van S. Hubbard, and Jack A. Yanovski).

References

1. The Diagnostic and Statistical Manual of Mental Disorders. 5th ed. ed. Arlington, VA: American Psychiatric Publishing; 2013.
1. Epel E, Jimenez S, Brownell K, Stroud L, Stoney C, Niaura R. Are stress eaters at risk for the metabolic syndrome? Ann N Y Acad Sci. 2004;1032:208–210. - PubMed
1. Fairburn CG, Cooper Z. The Eating Disorders Examination. In: Fairburn CG, GT W, editors. Binge Eating: Nature, Assessment, & Treatment. 12th Edition ed. New York, NY: Guilford; 1993. pp. 317–360.
1. Glasofer DR, Tanofsky-Kraff M, Eddy KT, Yanovski SZ, Theim KR, Mirch MC, Ghorbani S, Ranzenhofer LM, Haaga D, Yanovski JA. Binge eating in overweight treatment-seeking adolescents. J Pediatr Psychol. 2007;32:95–105. - PMC - PubMed
1. Gustafson JK, Yanoff LB, Easter BD, Brady SM, Keil MF, Roberts MD, Sebring NG, Han JC, Yanovski SZ, Hubbard VS, Yanovski JA. The stability of metabolic syndrome in children and adolescents. J Clin Endocrinol Metab. 2009;94:4828–4834. - PMC - PubMed

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Metabolic characteristics of youth with loss of control eating

Affiliations

Metabolic characteristics of youth with loss of control eating

Authors

Affiliations

Abstract

Conflict of interest statement

References

Publication types

MeSH terms

Substances

Associated data

Grants and funding

LinkOut - more resources

Full Text Sources

Other Literature Sources

Medical

Miscellaneous