Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Dec;30(12):2153-62.
doi: 10.1007/s00467-015-3159-6. Epub 2015 Jul 27.

Anxiety, depression, resilience and quality of life in children and adolescents with pre-dialysis chronic kidney disease

Janaina Matos Moreira  1 , Cristina Maria Bouissou Morais Soares  2 , Antônio Lúcio Teixeira  1 , Ana Cristina Simões E Silva  3   4 , Arthur Melo Kummer  1
Affiliations

Anxiety, depression, resilience and quality of life in children and adolescents with pre-dialysis chronic kidney disease

Janaina Matos Moreira et al. Pediatr Nephrol. 2015 Dec.

Abstract

Background: Chronic kidney disease (CKD) is a risk factor for psychosocial impairment and psychiatric symptoms. Children and adolescents on dialysis frequently have compromised daily life activities and a worse quality of life (QoL) compared with healthy peers. However, few studies have investigated these aspects of CKD in pediatric pre-dialysis CKD patients. Therefore, we have analyzed resilience, QoL and anxiety and depressive symptoms in children and adolescents with pre-dialysis CKD and compared these to the values of healthy controls.

Methods: Demographic and clinical data were collected from 28 children and adolescents with pre-dialysis CKD and 28 healthy sex- and age-matched controls. Psychological assessment of the participants was performed using the Wagnild and Young Resilience Scale, Pediatric Quality of Life (QoL) Inventory 4.0 , Child Depression Inventory and Self-report for Childhood Anxiety Related Disorders scales.

Results: Of the 56 children enrolled in our study, the CKD patients were referred to mental health professionals more frequently than the controls. Patients exhibited higher scores for separation anxiety and a higher frequency of clinically significant depressive symptoms. They also had lower overall QoL scores, as well as poorer scores for the psychological, educational and psychosocial subdomains of QoL instruments. There was a negative correlation between anxiety and depressive symptoms and all domains of QoL. Resilience was similar in both groups, but lower in patients with significant depressive symptoms. No significant association was found between clinical or laboratory findings and psychological variables in CKD patients.

Conclusion: Although patients and controls exhibited similar scores of resilience, CKD negatively impacted the QoL of pediatric patients, contributing to a higher frequency of depression and separation anxiety.

Keywords: Chronic kidney disease; Pediatric; Psychiatry; Quality of life; Resilience.

PubMed Disclaimer

References

    1. Am J Transplant. 2003 Nov;3(11):1418-25 - PubMed
    1. Clin J Am Soc Nephrol. 2008 Nov;3(6):1752-8 - PubMed
    1. ScientificWorldJournal. 2013 Mar 25;2013:124973 - PubMed
    1. J Pediatr Psychol. 1996 Feb;21(1):89-101 - PubMed
    1. Rev Assoc Med Bras (1992). 2011 Jul-Aug;57(4):436-41 - PubMed

Publication types