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Review
. 2015 Sep-Oct:51:35-44.
doi: 10.1016/j.ntt.2015.07.006. Epub 2015 Jul 23.

Developmental and behavioral consequences of prenatal methamphetamine exposure: A review of the Infant Development, Environment, and Lifestyle (IDEAL) study

Lynne M Smith  1 , Sabrina Diaz  2 , Linda L LaGasse  3 , Trecia Wouldes  4 , Chris Derauf  5 , Elana Newman  6 , Amelia Arria  7 , Marilyn A Huestis  8 , William Haning  5 , Arthur Strauss  9 , Sheri Della Grotta  3 , Lynne M Dansereau  3 , Charles Neal  4 , Barry M Lester  3
Affiliations
Review

Developmental and behavioral consequences of prenatal methamphetamine exposure: A review of the Infant Development, Environment, and Lifestyle (IDEAL) study

Lynne M Smith et al. Neurotoxicol Teratol. 2015 Sep-Oct.

Abstract

This study reviews the findings from the Infant Development, Environment, and Lifestyle (IDEAL) study, a multisite, longitudinal, prospective study designed to determine maternal outcome and child growth and developmental findings following prenatal methamphetamine exposure from birth up to age 7.5 years. These findings are presented in the context of the home environment and caregiver characteristics to determine how the drug and the environment interact to affect the outcome of these children. No neonatal abstinence syndrome requiring pharmacologic intervention was observed but heavy drug exposure was associated with increased stress responses in the neonatal period. Poorer inhibitory control was also observed in heavy methamphetamine exposed children placing them at high risk for impaired executive function. Independent of methamphetamine exposure, children with more responsive home environments to developmental and emotional needs demonstrated lower risks for internalizing and externalizing behavior.

Keywords: Longitudinal; Methamphetamine; Neurodevelopment; Prenatal exposure.

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Figures

Figure 1
Figure 1
Recruitment Flow Chart
Figure 2
Figure 2
Retention Percentages at each visit age-US IDEAL.
Figure 3
Figure 3
Retention Percentages at each Visit Age- NZ IDEAL
See this image and copyright information in PMC

References

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