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Randomized Controlled Trial
. 2015 Oct;136(4):1129-31.
doi: 10.1016/j.jaci.2015.06.011. Epub 2015 Jul 26.

Does azithromycin modify viral load during severe respiratory syncytial virus bronchiolitis?

Avraham Beigelman  1 , Leonard B Bacharier  2 , Jack Baty  3 , Richard Buller  2 , Sheila Mason  2 , Kenneth B Schechtman  3 , Geneline Sajol  4 , Megan Isaacson-Schmid  2 , Mario Castro  4 , Gregory A Storch  2
Affiliations
Randomized Controlled Trial

Does azithromycin modify viral load during severe respiratory syncytial virus bronchiolitis?

Avraham Beigelman et al. J Allergy Clin Immunol. 2015 Oct.
No abstract available

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Figures

Figure 1
Figure 1
Mean log10 RSV nasal lavage loads on randomization, day 8, and day 15 among the APW-RSV trial participants. * p<0.01.
See this image and copyright information in PMC

References

    1. Bacharier LB, Cohen R, Schweiger T, Yin-Declue H, Christie C, Zheng J, et al. Determinants of asthma after severe respiratory syncytial virus bronchiolitis. J Allergy Clin Immunol. 2012;130:91–100 e3. - PMC - PubMed
    1. Beigelman A, Bacharier LB. The role of early life viral bronchiolitis in the inception of asthma. Curr Opin Allergy Clin Immunol. 2013;13:211–6. - PMC - PubMed
    1. Escobar GJ, Masaquel AS, Li SX, Walsh EM, Kipnis P. Persistent recurring wheezing in the fifth year of life after laboratory-confirmed, medically attended respiratory syncytial virus infection in infancy. BMC Pediatr. 2013;13:97. - PMC - PubMed
    1. Beigelman A, Isaacson-Schmid M, Sajol G, Baty J, Rodriguez OM, Leege E, et al. Randomized trial to evaluate azithromycin's effects on serum and upper airway IL-8 levels and recurrent wheezing in infants with respiratory syncytial virus bronchiolitis. J Allergy Clin Immunol. 2015;135:1171–8 e1. - PMC - PubMed
    1. Gielen V, Johnston SL, Edwards MR. Azithromycin induces anti-viral responses in bronchial epithelial cells. Eur Respir J. 2010;36:646–54. - PubMed

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