Counting copy number and calories
- PMID: 26220133
- DOI: 10.1038/ng.3365
Counting copy number and calories
Abstract
Copy number variation (CNV) at several genomic loci has been associated with different human traits and diseases, but in many cases the findings could not be replicated. A new study provides insights into the degree of variation present at the amylase locus and calls into question a previous association between amylase copy number and body mass index.
Comment on
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Structural forms of the human amylase locus and their relationships to SNPs, haplotypes and obesity.Nat Genet. 2015 Aug;47(8):921-5. doi: 10.1038/ng.3340. Epub 2015 Jun 22. Nat Genet. 2015. PMID: 26098870 Free PMC article.
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