Biological Perspectives: Anti-NMDA Receptor Encephalitis

Abstract

Purpose: This article explores the recently recognized anti-NMDA receptor encephalitis, which may produce psychiatric symptoms.

Conclusions: Historically, some patients presenting for psychiatric care may have actually been suffering from anti-NMDA encephalitis; thus, awareness of this disorder may facilitate appropriate treatment.

Treatment implications: Early diagnosis and aggressive treatment promote better outcomes. First-line treatment includes immunotherapy.

Keywords: Encephalitis; NMDA receptors; glutamate.