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Review
. 2016 Mar;125(1):95-110.
doi: 10.1007/s00412-015-0534-9. Epub 2015 Jul 30.

Coming to terms with chromatin structure

Liron Even-Faitelson  1 , Vahideh Hassan-Zadeh  2 , Zahra Baghestani  1 , David P Bazett-Jones  3
Affiliations
Review

Coming to terms with chromatin structure

Liron Even-Faitelson et al. Chromosoma. 2016 Mar.

Abstract

Chromatin, once thought to serve only as a means to package DNA, is now recognized as a major regulator of gene activity. As a result of the wide range of methods used to describe the numerous levels of chromatin organization, the terminology that has emerged to describe these organizational states is often imprecise and sometimes misleading. In this review, we discuss our current understanding of chromatin architecture and propose terms to describe the various biochemical and structural states of chromatin.

Keywords: Accessibility; Chromatin; Compaction; Heterochromatin; Higher order chromatin organization; Structure.

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