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Comment
. 2015;14(18):2865-6.
doi: 10.1080/15384101.2015.1076302. Epub 2015 Jul 29.

The unpredictable consequences of CDKN1B/p27Kip1 mutations in cancer

Adriana Borriello  1 , Debora Bencivenga  1 , Fulvio Della Ragione  1
Affiliations
Comment

The unpredictable consequences of CDKN1B/p27Kip1 mutations in cancer

Adriana Borriello et al. Cell Cycle. 2015.
No abstract available

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Figures

Figure 1.
Figure 1.
The figure shows in the upper part the main p27Kip1 structural domains and their putative roles. At the bottom, the missense mutations so far identified are reported. The corresponding human neoplasia where they have been identified are also listed. mNPAP60, mouse Nuclear Pore Associated Protein. Nuc (nucleus) and Cyt (Cytosol). AIP− (AIP gene mutation-negative). The arrows show the putative interacting residues.
See this image and copyright information in PMC

Comment on

  • Recurrent CDKN1B (p27) mutations in hairy cell leukemia.
    Dietrich S, Hüllein J, Lee SC, Hutter B, Gonzalez D, Jayne S, Dyer MJ, Oleś M, Else M, Liu X, Słabicki M, Wu B, Troussard X, Dürig J, Andrulis M, Dearden C, von Kalle C, Granzow M, Jauch A, Fröhling S, Huber W, Meggendorfer M, Haferlach T, Ho AD, Richter D, Brors B, Glimm H, Matutes E, Abdel Wahab O, Zenz T. Dietrich S, et al. Blood. 2015 Aug 20;126(8):1005-8. doi: 10.1182/blood-2015-04-643361. Epub 2015 Jun 11. Blood. 2015. PMID: 26065650

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