Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Dec;36(12):2314-9.
doi: 10.3174/ajnr.A4445. Epub 2015 Jul 30.

WEB-DL Endovascular Treatment of Wide-Neck Bifurcation Aneurysms: Long-Term Results in a European Series

Affiliations

WEB-DL Endovascular Treatment of Wide-Neck Bifurcation Aneurysms: Long-Term Results in a European Series

L Pierot et al. AJNR Am J Neuroradiol. 2015 Dec.

Erratum in

  • Erratum.
    [No authors listed] [No authors listed] AJNR Am J Neuroradiol. 2016 Feb;37(2):E19. doi: 10.3174/ajnr.A4643. Epub 2015 Dec 17. AJNR Am J Neuroradiol. 2016. PMID: 26680465 Free PMC article. No abstract available.

Abstract

Background and purpose: Flow disruption with the WEB-DL device has been used safely for the treatment of wide-neck bifurcation aneurysms. The stability of aneurysm occlusion after this treatment was evaluated in the short and midterm, but not in the long term. This retrospective multicenter European study is the continuation of an already published series dealing with short- and midterm anatomic results and analyzes long-term data in patients treated with the WEB-DL.

Materials and methods: Twelve European neurointerventional centers initially participated in the study. In addition to data collected for the initial publication, images obtained at long-term follow-up were collected and independently analyzed by the same experienced interventional neuroradiologist.

Results: Of the initial 45 patients, 26 (20 women and 6 men; 35-73 years of age; mean, 55.2 ± 10.6 years; median, 55.5 years) with 26 aneurysms treated with the WEB-DL device had long-term follow-up (median, 27.4 months). Three of 26 patients (11.5%) were retreated between short- and midterm follow-up, and none, between mid- and long-term follow-up. Long-term aneurysm occlusion in the 19 patients treated with the WEB only and not retreated during follow-up was complete occlusion in 13/19 patients (68.4%), including aneurysms with opacification of the proximal recess in 9/19 patients (47.4%), neck remnant in 3/19 patients (15.8%), and aneurysm remnant in 3/19 patients (15.8%). In all patients (100.0%), aneurysm occlusion was stable between midterm and long-term follow-up.

Conclusions: The results suggest that WEB treatment of wide-neck bifurcation aneurysms offers long-term stable occlusion.

PubMed Disclaimer

Figures

Fig 1.
Fig 1.
A, Preoperative DSA shows a wide-neck middle cerebral artery aneurysm with a daughter sac. B and C, Three- and 12-month DSA show complete aneurysm occlusion. D, Twenty-seven-month MRA shows complete aneurysm occlusion.
Fig 2.
Fig 2.
A, Preoperative DSA shows a wide-neck anterior communicating artery aneurysm. B–D, Six-, 12-, and 26-month DSA show stable complete aneurysm occlusion with opacification of the proximal recess.
Fig 3.
Fig 3.
A, Preoperative DSA shows a wide-neck basilar artery aneurysm. B, The WEB device is deployed in the aneurysm. C and D, Six-month DSA (oblique and lateral views) shows a small aneurysm remnant. E and F, Twenty-one-month DSA (oblique and lateral views) shows that the aneurysm remnant has not grown.

References

    1. Molyneux A, Kerr R, Stratton I, et al. ; International Subarachnoid Aneurysm Trial (ISAT) Collaborative Group. International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trial. Lancet 2002;360:1267–74 10.1016/S0140-6736(02)11314-6 - DOI - PubMed
    1. McDougall CG, Spetzler RF, Zabramski JM, et al. . The Barrow Ruptured Aneurysm Trial. J Neurosurg 2012;116:135–44 10.3171/2011.8.JNS101767 - DOI - PubMed
    1. Cognard C, Pierot L, Anxionnat R, et al. ; Clarity Study Group. Results of embolization used as the first treatment choice in a consecutive nonselected population of ruptured aneurysms: clinical results of the Clarity GDC study. Neurosurgery 2011;69:837–41; discussion 842 10.1227/NEU.0b013e3182257b30 - DOI - PubMed
    1. Pierot L, Spelle L, Vitry F; ATENA Investigators. Immediate clinical outcome of patients harboring unruptured intracranial aneurysms treated by endovascular approach: results of the ATENA study. Stroke 2008;39:2497–504 10.1161/STROKEAHA.107.512756 - DOI - PubMed
    1. Pierot L, Wakhloo A. Endovascular treatment of intracranial aneurysms: current status. Stroke 2013;44:2046–54 10.1161/STROKEAHA.113.000733 - DOI - PubMed