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Case Reports
. 2015 Jul 31:2015:bcr2015210138.
doi: 10.1136/bcr-2015-210138.

Clinicopathological significance of Melkersson-Rosenthal syndrome

Shruti Bohra  1 , Pratik B Kariya  2 , Seema Dinesh Bargale  2 , Shital Kiran  3
Affiliations
Case Reports

Clinicopathological significance of Melkersson-Rosenthal syndrome

Shruti Bohra et al. BMJ Case Rep. .

Abstract

Melkersson-Rosenthal syndrome (MRS) classically shows a triad of orofacial swelling, fissured tongue and facial palsy, more commonly the oligosymptomatic form. The orofacial swelling is characterised by swollen reddish-brown non-pruritic lips and facial oedema. In one-third to one half of patients, fissured tongue is seen, which also aids in diagnosis. The histological finding of MRS includes non-caseating, sarcoidal granulomas, but their absence does not exclude the diagnosis. All these findings together form a basis for a cautious search for confrontational reasons for the symptom complex of MRS.

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Figures

Figure 1
Figure 1
Extraoral photograph showing swollen upper and lower lips.
Figure 2
Figure 2
Intraoral photograph showing generalised gingival enlargement.
Figure 3
Figure 3
Intraoral photograph showing deep grooves on dorsal surface of the tongue.
Figure 4
Figure 4
Photograph showing histological presentation of cheilitis glanduralis at low power (10×) and high power (40×).
See this image and copyright information in PMC

References

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