Earlier treatment of NMDAR antibody encephalitis in children results in a better outcome

Affiliations

¹ Children's Neurosciences (S.B., M.L.), Evelina London Children's Hospital, Kings Health Partners Academic Health Science Center, UK; Department of Pediatric Neurology (S.B., M.K.), Children's University Hospital, Temple Street, Dublin, Ireland; Department of Statistics (C.W.), Trinity College, Dublin, Ireland; Nuffield Department of Clinical Neurosciences (Y.H., A.V., M.L.), John Radcliffe University Hospital, Oxford, England; Texas Children's Hospital (E.M., J.J., A.S.), Baylor College of Medicine, Houston, TX; Neuroimmunology Group (R.C.D.), Institute for Neuroscience and Muscle Research, The Kids Research Institute at the Children's Hospital at Westmead, University of Sydney, Australia; and TY Nelson Department of Neurology and Neurosurgery (R.C.D.), Children's Hospital at Westmead, Sydney, Australia.

Susan Byrne et al. Neurol Neuroimmunol Neuroinflamm. 2015.

. 2015 Jul 23;2(4):e130.

doi: 10.1212/NXI.0000000000000130. eCollection 2015 Aug.

¹ Children's Neurosciences (S.B., M.L.), Evelina London Children's Hospital, Kings Health Partners Academic Health Science Center, UK; Department of Pediatric Neurology (S.B., M.K.), Children's University Hospital, Temple Street, Dublin, Ireland; Department of Statistics (C.W.), Trinity College, Dublin, Ireland; Nuffield Department of Clinical Neurosciences (Y.H., A.V., M.L.), John Radcliffe University Hospital, Oxford, England; Texas Children's Hospital (E.M., J.J., A.S.), Baylor College of Medicine, Houston, TX; Neuroimmunology Group (R.C.D.), Institute for Neuroscience and Muscle Research, The Kids Research Institute at the Children's Hospital at Westmead, University of Sydney, Australia; and TY Nelson Department of Neurology and Neurosurgery (R.C.D.), Children's Hospital at Westmead, Sydney, Australia.

No abstract available

References

1. Titulaer MJ, McCracken L, Gabilondo I, et al. Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study. Lancet Neurol 2013;12:157–165. - PMC - PubMed
1. Irani SR, Bera K, Waters P, et al. N-methyl-D-aspartate antibody encephalitis: temporal progression of clinical and paraclinical observations in a predominantly non-paraneoplastic disorder of both sexes. Brain 2010;133:1655–1667. - PMC - PubMed
1. Moscato EH, Peng X, Jain A, Parsons TD, Dalmau J, Balice-Gordon RJ. Acute mechanisms underlying antibody effects in anti-N-methyl-D-aspartate receptor encephalitis. Ann Neurol 2014;76:108–119. - PMC - PubMed
1. Mikasova L, De Rossi P, Bouchet D, et al. Disrupted surface cross-talk between NMDA and Ephrin-B2 receptors in anti-NMDA encephalitis. Brain 2012;135:1606–1621. - PubMed
1. Finke C, Kopp UA, Scheel M, et al. Functional and structural brain changes in anti-N-methyl-D-aspartate receptor encephalitis. Ann Neurol 2013;74:284–296. - PubMed