The Treatment of Verrucae Pedis Using Falknor's Needling Method: A Review of 46 Cases
- PMID: 26236985
- PMCID: PMC4470114
- DOI: 10.3390/jcm2020013
The Treatment of Verrucae Pedis Using Falknor's Needling Method: A Review of 46 Cases
Abstract
Human Papilloma Virus (HPV) related verrucae pedis persist, seemingly evading host immune surveillance, yet sometimes disappear with inflammation. The absence, or reduction, of a cellular immune response may explain why verrucae treatments are not uniformly successful and treatment can be difficult even in immune-competent individuals. Little investigation has been undertaken into the potential benefit and efficacy of needling verrucae, a treatment modality causing HPV infected keratinocyte destruction in addition to inducing an assumed enhanced immune response. A review of clinical practice is presented, reporting the treatment method and results of data collected from a retrospective review of 45 patients. Thirty-one (69%) cases demonstrated complete resolution of verrucae following needling treatment. Three patients demonstrated reduction in size and pain whilst 11 showed no improvement. No adverse events were noted. Needling may have a place in the management of verrucae pedis in an adult population but a large scale study utilising objective measures and a control intervention would provide more detailed efficacy data along with a greater understanding of the effects of this treatment on long term immunity.
Keywords: HPV; foot; infection; plantar; verrucae; virus; wart.
Figures
Similar articles
-
EVerT2-needling versus non-surgical debridement for the treatment of verrucae: study protocol for a single-centre randomised controlled trial.BMJ Open. 2015 Nov 24;5(11):e009406. doi: 10.1136/bmjopen-2015-009406. BMJ Open. 2015. PMID: 26603251 Free PMC article. Clinical Trial.
-
The EVerT2 (Effective Verruca Treatments 2) trial: a randomized controlled trial of needling vs. nonsurgical debridement for the treatment of plantar verrucae.Br J Dermatol. 2017 Nov;177(5):1285-1292. doi: 10.1111/bjd.15751. Epub 2017 Nov 1. Br J Dermatol. 2017. PMID: 28653324 Clinical Trial.
-
Falknor's needling method as a potential immunotherapy in palmo-plantar warts.Indian J Dermatol Venereol Leprol. 2019 Jan-Feb;85(1):129. doi: 10.4103/ijdvl.IJDVL_809_17. Indian J Dermatol Venereol Leprol. 2019. PMID: 30467272
-
Needling for the Treatment of Warts.Skinmed. 2020 Mar 1;18(2):91-93. eCollection 2020. Skinmed. 2020. PMID: 32501791 Review.
-
The Human Papillomavirus and Its Role in Plantar Warts: A Comprehensive Review of Diagnosis and Management.Clin Podiatr Med Surg. 2016 Jul;33(3):337-53. doi: 10.1016/j.cpm.2016.02.003. Epub 2016 Mar 29. Clin Podiatr Med Surg. 2016. PMID: 27215155 Review.
Cited by
-
EVerT2-needling versus non-surgical debridement for the treatment of verrucae: study protocol for a single-centre randomised controlled trial.BMJ Open. 2015 Nov 24;5(11):e009406. doi: 10.1136/bmjopen-2015-009406. BMJ Open. 2015. PMID: 26603251 Free PMC article. Clinical Trial.
-
Treatment of Plantar Warts with a Nitric-Zinc Complex Solution: A Review of 72 Cases.Viruses. 2024 Aug 16;16(8):1307. doi: 10.3390/v16081307. Viruses. 2024. PMID: 39205281 Free PMC article.
-
Falkner's needling technique for the treatment of warts: Minimum investment, maximum benefit.Med J Armed Forces India. 2022 Sep;78(Suppl 1):S75-S81. doi: 10.1016/j.mjafi.2020.07.009. Epub 2020 Oct 9. Med J Armed Forces India. 2022. PMID: 36147396 Free PMC article.
-
The efficacy of cryotherapy compared to other modalities in the management of palmoplantar warts: a systematic review and network meta-analysis.Dermatol Reports. 2025 May 23;17(2):10121. doi: 10.4081/dr.2024.10121. Epub 2024 Oct 25. Dermatol Reports. 2025. PMID: 40586422 Free PMC article.
-
Clinical Resolution of Plantar Warts Using the Needling Technique.Diseases. 2025 Feb 7;13(2):50. doi: 10.3390/diseases13020050. Diseases. 2025. PMID: 39997057 Free PMC article.
References
-
- Gibbs S., Harvey I. Cochrane Database of Systematic Reviews. John Wiley & Sons; Chichester, UK: 2006. Topical treatments for cutaneous warts. - PubMed
-
- Falknor G.W. Needling—a new technique in verruca therapy. A case report. J. Am. Podiatry Assoc. 1969;59:51–52. - PubMed
-
- Colver G. Cryosurgery in podiatric practice. Podiatry Now. 2005;8:S1–S8.
LinkOut - more resources
Full Text Sources
Other Literature Sources