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Review
. 2014 Jul 29;3(3):865-82.
doi: 10.3390/jcm3030865.

Screening and Invasive Testing in Twins

Giovanni Monni  1 , Ambra Iuculano  2 , Maria Angelica Zoppi  3
Affiliations
Review

Screening and Invasive Testing in Twins

Giovanni Monni et al. J Clin Med. .

Abstract

Prenatal screening and testing for trisomy 21 in twin pregnancies poses a number of challenges: the exact estimate of the a priori risk of trisomy 21, the choice of prenatal screening test and/or invasive techniques to employ for the diagnosis and the impact of the result on the options of treatment in case of discordant results within a twin pair or among multiples. These different aspects are discussed below while recognizing that many issues remain unresolved.

Keywords: invasive diagnosis; screening; therapy; twins.

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References

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