Tropical and travel-associated norovirus: current concepts
- PMID: 26237546
- PMCID: PMC4635028
- DOI: 10.1097/QCO.0000000000000197
Tropical and travel-associated norovirus: current concepts
Abstract
Purpose of review: We highlight recent advances relevant to understanding norovirus infections in the tropics, both in populations living in developing settings and travelers to these regions.
Recent findings: Because of the decrease in diarrheal disease associated with the global rollout of vaccines against rotavirus, norovirus is emerging as the predominant cause of diarrhea morbidity among children in the tropics, and evidence suggests that it contributes to adult disease in endemic populations and travelers. In addition to identifying potential target populations for preventive measures, we provide an update on norovirus vaccine development and concepts related to their implementation in low-income and middle-income countries.
Summary: These current concepts related to norovirus-attributable disease burden, clinical significance, and economic impact can potentially be applied to tailoring efforts to prevent and mitigate the effects of this important enteropathogen.
Conflict of interest statement
There are no conflicts of interest.
References
-
- Pringle K, Lopman B, Vega E, et al. Noroviruses: epidemiology, immunity and prospects for prevention. Future Microbiol. 2015;10:53–67. - PubMed
-
- Ahmed SM, Hall AJ, Robinson AE, et al. Global prevalence of norovirus in cases of gastroenteritis: a systematic review and meta-analysis. Lancet Infect Dis. 2014;14:725–730. Systematic review and meta-analysis of norovirus reports from 2008 to 2014 estimating the pooled prevalences of symptomatic and asymptomatic individiuals in various clinical and socioeconomic settings. - PMC - PubMed
-
- Beaglehold RAI, Prentice T. The world health report 2003: shaping the future. Geneva: World Health Organization; 2003.
-
- Saito M, Goel-Apaza S, Espetia S, et al. Multiple norovirus infections in a birth cohort in a Peruvian periurban community. Clin Infect Dis. 2014;58:483–491. High-quality Peruvian birth cohort study reporting norovirus incidence, excretion duration, viral genotypes, and length for age z scores in infected versus uninfected children. - PMC - PubMed
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Medical
Research Materials
