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Comment
. 2015 Aug;17(8):964-5.
doi: 10.1038/ncb3212.

Condensing chromosome condensation

Jason C Bell  1 , Aaron F Straight  1
Affiliations
Comment

Condensing chromosome condensation

Jason C Bell et al. Nat Cell Biol. 2015 Aug.

Abstract

Mitotic chromosome condensation has fascinated biologists since Flemming's early illustrations of mitosis in the late nineteenth century. Now--130 years later--chromatid condensation is reconstituted in vitro with the minimum components. The results are remarkably and beautifully simple, requiring only core histones, three histone chaperones, topoisomerase II and condensin I.

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References

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