Building stomach in a dish
- PMID: 26239528
- DOI: 10.1038/ncb3211
Building stomach in a dish
Abstract
Modelling organs in culture has great potential to improve our understanding of development, organogenesis and disease. While some endodermal derived organs have been modelled, the corpus region of the stomach, where acid-producing cells reside, remained an invincible target. A 60-day differentiation protocol now enables the generation of functional acid-producing cells in culture, conquering the challenge.
Comment on
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Generation of stomach tissue from mouse embryonic stem cells.Nat Cell Biol. 2015 Aug;17(8):984-93. doi: 10.1038/ncb3200. Epub 2015 Jul 20. Nat Cell Biol. 2015. PMID: 26192439
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