Antipsychotic Maintenance Treatment: Time to Rethink?
- PMID: 26241954
- PMCID: PMC4524699
- DOI: 10.1371/journal.pmed.1001861
Antipsychotic Maintenance Treatment: Time to Rethink?
Abstract
Joanna Moncrieff looks at the lack of long-term evidence for antipsychotic medication and considers what is needed to ensure we have the knowledge to maximize benefits and minimize harms.
Conflict of interest statement
I have read the journal's policy and have the following conflicts: I am a member and co-chairman of the Critical Psychiatry Network (
Similar articles
-
Choice of maintenance medication for schizophrenia.J Clin Psychiatry. 2003;64 Suppl 16:24-33. J Clin Psychiatry. 2003. PMID: 14680416 Review.
-
Intermittent medication--an alternative?Acta Psychiatr Scand Suppl. 1994;382:33-8. doi: 10.1111/j.1600-0447.1994.tb05863.x. Acta Psychiatr Scand Suppl. 1994. PMID: 7916527 Review.
-
Is there rebound psychosis on withdrawal of antipsychotic medication in schizophrenia?Schizophr Res. 2018 Nov;201:430-431. doi: 10.1016/j.schres.2018.06.008. Epub 2018 Jun 8. Schizophr Res. 2018. PMID: 29887253 No abstract available.
-
Switch or stay?Am J Psychiatry. 2006 Dec;163(12):2032-3. doi: 10.1176/ajp.2006.163.12.2032. Am J Psychiatry. 2006. PMID: 17151147 No abstract available.
-
Treating prodromal episodes to prevent relapse in schizophrenia.Br J Psychiatry Suppl. 1989 Jul;(5):123-7. Br J Psychiatry Suppl. 1989. PMID: 2574984 Clinical Trial. No abstract available.
Cited by
-
The debate regarding maintenance treatment with antipsychotic drugs in schizophrenia.Dialogues Clin Neurosci. 2018 Sep;20(3):215-221. doi: 10.31887/DCNS.2018.20.3/mdavidson. Dialogues Clin Neurosci. 2018. PMID: 30581291 Free PMC article.
-
Metacognitive Reflection and Insight Therapy: A Recovery-Oriented Treatment Approach for Psychosis.Psychol Res Behav Manag. 2020 Apr 2;13:331-341. doi: 10.2147/PRBM.S198628. eCollection 2020. Psychol Res Behav Manag. 2020. PMID: 32308511 Free PMC article. Review.
-
Collaborative care approaches for people with severe mental illness.Cochrane Database Syst Rev. 2024 May 7;5(5):CD009531. doi: 10.1002/14651858.CD009531.pub3. Cochrane Database Syst Rev. 2024. PMID: 38712709 Free PMC article. Review.
-
An analysis of views about supported reduction or discontinuation of antipsychotic treatment among people with schizophrenia and other psychotic disorders.BMC Psychiatry. 2022 Mar 15;22(1):185. doi: 10.1186/s12888-022-03822-5. BMC Psychiatry. 2022. PMID: 35291964 Free PMC article.
-
Improving life expectancy in people with serious mental illness: should we place more emphasis on primary prevention?Br J Psychiatry. 2017 Oct;211(4):194-197. doi: 10.1192/bjp.bp.117.203240. Epub 2017 Sep 7. Br J Psychiatry. 2017. PMID: 28882826 Free PMC article.
References
-
- Rossler W, Salize HJ, van Os J, Riecher-Rossler A. Size of burden of schizophrenia and psychotic disorders. Eur Neuropsychopharmacol 2005. August;15(4):399–409. - PubMed
-
- Wu EQ, Birnbaum HG, Shi L, Ball DE, Kessler RC, Moulis M, et al. The economic burden of schizophrenia in the United States in 2002. J Clin Psychiatry 2005. September;66(9):1122–9. - PubMed
-
- Wiersma D, Wanderling J, Dragomirecka E, Ganev K, Harrison G, an der HW, et al. Social disability in schizophrenia: its development and prediction over 15 years in incidence cohorts in six European centres. Psychol Med 2000. September;30(5):1155–67. - PubMed
-
- CRANE GE. Clinical psychopharmacology in its 20th year. Late, unanticipated effects of neuroleptics may limit their use in psychiatry. Science 1973. July 13;181(4095):124–8. - PubMed
-
- Royal College of Psychiatrists. Report of the Second Round of the National Audit of Schizophrenia (NAS) 2014. London: Healthcare Quality Improvement Partnership; 2014.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical