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Comment
. 2015 Aug 5;87(3):468-70.
doi: 10.1016/j.neuron.2015.07.022.

Norepinephrine and Corticotropin-Releasing Hormone: Partners in the Neural Circuits that Underpin Stress and Anxiety

Yajie Sun  1 , Sarah Hunt  1 , Pankaj Sah  2
Affiliations
Comment

Norepinephrine and Corticotropin-Releasing Hormone: Partners in the Neural Circuits that Underpin Stress and Anxiety

Yajie Sun et al. Neuron. .

Abstract

Norepinephrine and corticotropin-releasing hormone (CRH) have long been implicated in the response to stress. In this issue of Neuron, McCall et al. (2015) show that CRH projections from the central amygdala drive tonic locus coeruleus activity that evokes acute anxiety responses and place aversion.

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