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Review
. 2017 Sep 2;57(13):2737-2748.
doi: 10.1080/10408398.2015.1060190.

Conjugated linoleic acid: A potent fatty acid linked to animal and human health

Parisa Shokryzadan  1   2 , Mohamed Ali Rajion  1 , Goh Yong Meng  1   3 , Liang Juan Boo  3 , Mahdi Ebrahimi  1 , Maryam Royan  4 , Mahbod Sahebi  3 , Parisa Azizi  3 , Rambod Abiri  5 , Mohammad Faseleh Jahromi  2   3
Affiliations
Review

Conjugated linoleic acid: A potent fatty acid linked to animal and human health

Parisa Shokryzadan et al. Crit Rev Food Sci Nutr. .

Abstract

Conjugated linoleic acid (CLA) is a mixture of isomers of linoleic acid (C18:2 n-6), which is mostly found in the ruminant meat and dairy products. The CLA is known to have many potential health benefits, and considered a potent powerful fatty acid, which is linked to animal and human health. The present work aims to discuss the source and production, mechanism of action, and effects of CLA on humans, poultry, and ruminants by reviewing the recent studies carried out on CLA. Despite most of the recent studies indicating beneficial effects of CLA on improving body weight control parameters, its effects on reducing risk factors of cardiovascular diseases (CVD), inflammation, blood glucose, and insulin are still controversial, and need to be further studied in different hosts.

Keywords: Conjugated linoleic acid; human; poultry; ruminant.

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