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Randomized Controlled Trial
. 2015 Sep;109(3):e32-5.
doi: 10.1016/j.diabres.2015.05.030. Epub 2015 May 15.

Effect of low dose pioglitazone on glycemic control and insulin resistance in Type 2 diabetes: A randomized, double blind, clinical trial

Sujit Rajagopalan  1 , Pinaki Dutta  2 , Debasish Hota  3 , Anil Bhansali  4 , Anand Srinivasan  5 , Amitava Chakrabarti  1
Affiliations
Randomized Controlled Trial

Effect of low dose pioglitazone on glycemic control and insulin resistance in Type 2 diabetes: A randomized, double blind, clinical trial

Sujit Rajagopalan et al. Diabetes Res Clin Pract. 2015 Sep.

Abstract

This study shows that pioglitazone 7.5 mg/day as an add-on therapy in Southeast Asian patients with Type 2 diabetes is safer and equally efficacious as the 15- and 30-mg doses of pioglitazone. Hence it is prudent to start pioglitazone therapy at a lower dose of 7.5 mg/day.

Keywords: Insulin resistance; Low dose; Pioglitazone; Thiazolidinediones; Type 2 diabetes.

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