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. 2015 Sep-Oct;19(5):492-7.
doi: 10.1016/j.bjid.2015.06.005. Epub 2015 Aug 5.

Chronic symptoms and pulmonary dysfunction in post-tuberculosis Brazilian patients

Simone de Sousa Elias Nihues  1 , Eliane Viana Mancuzo  2 , Nara Sulmonetti  2 , Flávia Patussi Correia Sacchi  3 , Vanessa de Souza Viana  2 , Eduardo Martins Netto  4 , Silvana Spindola Miranda  2 , Julio Croda  5
Affiliations

Chronic symptoms and pulmonary dysfunction in post-tuberculosis Brazilian patients

Simone de Sousa Elias Nihues et al. Braz J Infect Dis. 2015 Sep-Oct.

Abstract

Background: Questionnaire and spirometry were applied to post-tuberculosis indigenous and non-indigenous individuals from Dourados, Brazil, to investigate the prevalence of chronic respiratory symptoms and pulmonary dysfunction.

Methods: This was a cross-sectional study in cured tuberculosis individuals as reported in the National System on Reportable Diseases (SINAN) from 2002 to 2012.

Results: One hundred and twenty individuals were included in the study and the prevalence of chronic respiratory symptoms was 45% (95% CI, 34-59%). Respiratory symptoms included cough (28%), sputum (23%), wheezing (22%) and dyspnea (8%). These symptoms were associated with alcoholism, AOR: 3.1 (1.2-8.4); less than 4 years of schooling, AOR: 5.0 (1.4-17.7); and previous pulmonary diseases, AOR: 5.4 (1.7-17.3). Forty-one percent (95% CI, 29-56) had pulmonary disorders, of which the most prevalent were obstructive disorders (49%), followed by obstructive disorder with reduced forced vital capacity disorders (46%) and restrictive disorders (5%). The lifestyle difference could not explain differences in chronic symptoms and/or the prevalence of pulmonary dysfunction.

Conclusion: The high prevalence of chronic respiratory symptoms and pulmonary dysfunction in post-tuberculosis patients indicates a need for further interventions to reduce social vulnerability of patients successfully treated for tuberculosis.

Keywords: Brazil; Dysfunction; Spirometry; Tuberculosis.

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Figures

Fig. 1
Fig. 1
Flow chart of individuals with a history of tuberculosis in Dourados, Mato Grosso do Sul.
See this image and copyright information in PMC

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