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Review
. 2015 Mar-Apr;87(2):26-40.
doi: 10.15407/ubj87.02.026.

[ASSOCIATION OF ALLELE VARIANTS OF RECEPTOR GENE OF ANDROGENS (BY THE NUMBER OF CAG-REPEATS) WITH ANDROGEN DEPENDENT HORMONAL METABOLIC INDICES OF THE ORGANISM]

[Article in Ukrainian]
V V Korpachev, S V Melnychenko, R G Lukashova
Review

[ASSOCIATION OF ALLELE VARIANTS OF RECEPTOR GENE OF ANDROGENS (BY THE NUMBER OF CAG-REPEATS) WITH ANDROGEN DEPENDENT HORMONAL METABOLIC INDICES OF THE ORGANISM]

[Article in Ukrainian]
V V Korpachev et al. Ukr Biochem J. 2015 Mar-Apr.

Abstract

This review discusses up-to-date conceptions concerning an association of androgen receptor gene (AR) allele (by the number of CAG-repeats) variations with the change of the receptor activity in humans. Different contradictory experiment results concerning the AR function dependence on the number of CAG-repeats have been analyzed. The authors discuss this problem paying mostly their attention to the interrelation between the number of CAG-repeats and indicators of glucose and lipid metabolism in males and females.

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