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. 2015 Dec:36:88-90.
doi: 10.1016/j.anaerobe.2015.07.009. Epub 2015 Aug 6.

Antibiotic profiling of Clostridium difficile ribotype 176--A multidrug resistant relative to C. difficile ribotype 027

Marcela Krutova  1 , Jana Matejkova  2 , Jan Tkadlec  2 , Otakar Nyc  2
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Antibiotic profiling of Clostridium difficile ribotype 176--A multidrug resistant relative to C. difficile ribotype 027

Marcela Krutova et al. Anaerobe. 2015 Dec.

Abstract

Antibiotic profiling of twenty Czech Clostridium difficile PCR-ribotype 176 isolates revealed a high level of resistance to erythromycin, ciprofloxacin and moxifloxacin (n = 20) and to rifampicin (n = 13). Accumulation of resistance mechanisms to multiple antibiotics highlight that PCR-ribotype 176 belong to problematic epidemic strains.

Keywords: Clostridium difficile; Erythromycin; Moxifloxacin; PCR-ribotype 176; Resistance; Rifampicin; Thr82Ile.

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