Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015:2015:901214.
doi: 10.1155/2015/901214. Epub 2015 Jul 14.

Severe Hyperthyroidism Presenting with Acute ST Segment Elevation Myocardial Infarction

Dayan Zhou  1 , Zongjie Qu  1 , Hao Wang  1 , Zhe Wang  1 , Qiang Xu  1
Affiliations

Severe Hyperthyroidism Presenting with Acute ST Segment Elevation Myocardial Infarction

Dayan Zhou et al. Case Rep Cardiol. 2015.

Abstract

Introduction. Acute myocardial infarction is life-threatening. A cardiac troponin rise accompanied by typical symptoms, ST elevation or depression is diagnostic of acute myocardial infarction. Here, we report an unusual case of a female who was admitted with chest pain. However, she did not present with a typical profile of an acute myocardial infarction patient. Case Presentation. A 66-year-old Han nationality female presented with chest pain. The electrocardiogram (ECG) revealed arched ST segment elevations and troponin was elevated. However, the coronary angiography showed a normal coronary arterial system. Thyroid function tests showed that this patient had severe hyperthyroidism. Conclusion. Our case highlights the possibility that hyperthyroidism may cause a large area of myocardium injury and ECG ST segment elevation. We suggest routine thyroid function testing in patients with chest pain.

PubMed Disclaimer

Figures

Figure 1
Figure 1
ECG upon arrival at hospital.
Figure 2
Figure 2
ECG 11 days after admission.
Figure 3
Figure 3
ECG 2 weeks after discharge from hospital.
See this image and copyright information in PMC

References

    1. Alpert J. S., Thygesen K., Antman E., Bassand J. P. Myocardial infarction redefined—a consensus document of the Joint European Society of Cardiology/American College of Cardiology Committee for the redefinition of myocardial infarction. Journal of the American College of Cardiology. 2000;36(3):959–969. - PubMed
    1. Lewandowski K. C., Rechciński T., Krzemińska-Pakuła M., Lewiński A. Acute myocardial infarction as the first presentation of thyrotoxicosis in a 31-year old woman—case report. Thyroid Research. 2010;3(1, article 1) doi: 10.1186/1756-6614-3-1. - DOI - PMC - PubMed
    1. Al Jaber J., Haque S., Noor H., Ibrahim B., Al Suwaidi J. Thyrotoxicosis and coronary artery spasm: case report and review of the literature. Angiology. 2010;61(8):807–812. doi: 10.1177/0003319710365146. - DOI - PubMed
    1. Horne M. K., III, Singh K. K., Rosenfeld K. G., et al. Is thyroid hormone suppression therapy prothrombotic? Journal of Clinical Endocrinology and Metabolism. 2004;89(9):4469–4473. doi: 10.1210/jc.2004-0536. - DOI - PubMed
    1. Franklyn J. A., Maisonneuve P., Sheppard M. C., Betteridge J., Boyle P. Mortality after the treatment of hyperthyroidism with radioactive iodine. The New England Journal of Medicine. 1998;338(11):712–718. doi: 10.1056/nejm199803123381103. - DOI - PubMed

LinkOut - more resources