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. 2016 Jan;10(1):133-9.
doi: 10.5009/gnl14506.

Visceral Obesity Is Associated with Gallbladder Polyps

Jun Kyu Lee  1 , Suk Jae Hahn  1 , Hyoun Woo Kang  1 , Jae Gu Jung  1 , Han Seok Choi  1 , Jin Ho Lee  1 , In Woong Han  2 , Jin-Hee Jung  3 , Jae Hyun Kwon  3
Affiliations

Visceral Obesity Is Associated with Gallbladder Polyps

Jun Kyu Lee et al. Gut Liver. 2016 Jan.

Abstract

Background/aims: Gallbladder polyps (GBP) are a common clinical finding and may possess malignant potential. We conducted this study to determine whether visceral obesity is a risk factor for GBP.

Methods: We retrospectively reviewed records of subjects who received both ultrasonography and computed tomography with measurements of the areas of visceral adipose tissue and total adipose tissue (TAT) on the same day as health checkups.

Results: Ninety-three of 1,615 subjects (5.8%) had GBP and were compared with 186 age- and sex-matched controls. VAT (odds ratio [OR], 2.941; 95% confidence interval [CI], 1.325 to 6.529; p=0.008 for the highest quartile vs. the lowest quartile) and TAT (OR, 3.568; 95% CI, 1.625 to 7.833; p=0.002 for the highest quartile vs. the lowest quartile) were independent risk factors together with hypertension (OR, 2.512; 95% CI, 1.381 to 4.569; p=0.003), diabetes mellitus (OR, 2.942; 95% CI, 1.061 to 8.158; p=0.038), hepatitis B virus positivity (OR, 3.548; 95% CI, 1.295 to 9.716; p=0.014), and a higher level of total cholesterol (OR, 2.232; 95% CI, 1.043 to 4.778; p=0.039 for.

Conclusions: Visceral obesity measured by VAT and TAT was associated with GBP irrespective of body mass index or waist circumference.

Keywords: Adipose tissue; Gallbladder polyp; Metabolic syndrome; Obesity, abdominal; Risk factors.

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Figures

Fig. 1
Fig. 1
Measurement of visceral obesity. The areas of visceral adipose tissue (A) and total adipose tissue (B) were measured using computed tomography at the umbilicus level.
Fig. 2
Fig. 2
Flow chart showing selection of the study population.
Fig. 3
Fig. 3
A scatter plot showing the relationship between the sizes of gallbladder polyps and total adipose tissue.
Fig. 4
Fig. 4
A scatter plot showing the relationship between the sizes of gallbladder polyps and visceral adipose tissue.
See this image and copyright information in PMC

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