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Review
. 2015 Aug 6;6(3):59-72.
doi: 10.4292/wjgpt.v6.i3.59.

Antioxidants in liver health

Sael Casas-Grajales  1 , Pablo Muriel  1
Affiliations
Review

Antioxidants in liver health

Sael Casas-Grajales et al. World J Gastrointest Pharmacol Ther. .

Abstract

Liver diseases are a worldwide medical problem because the liver is the principal detoxifying organ and maintains metabolic homeostasis. The liver metabolizes various compounds that produce free radicals (FR). However, antioxidants scavenge FR and maintain the oxidative/antioxidative balance in the liver. When the liver oxidative/antioxidative balance is disrupted, the state is termed oxidative stress. Oxidative stress leads to deleterious processes in the liver and produces liver diseases. Therefore, restoring antioxidants is essential to maintain homeostasis. One method of restoring antioxidants is to consume natural compounds with antioxidant capacity. The objective of this review is to provide information pertaining to various antioxidants found in food that have demonstrated utility in improving liver diseases.

Keywords: Antioxidant; Coffee; Curcumin; Liver diseases; Naringenin; Oxidative stress; Quercetin; Resveratrol; Silymarin.

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Figures

Figure 1
Figure 1
Comparison between hepatoprotective effect-related antioxidant capacities. 1The structure presented is based on the most studied compound. For silymarin we show the structure of silybin, in the case of green tea the structure of (-)-epigallocatechin-3-gallate, and in the case of coffee the structure of caffeine.
See this image and copyright information in PMC

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