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Case Reports
. 2015 Aug 12:16:134.
doi: 10.1186/s12882-015-0133-2.

Impact of nocturnal hemodialysis on peripheral uremic neuropathy

Sassan Ghazan-Shahi  1 , Timothy Jee Kam Koh  2 , Christopher T Chan  3
Affiliations
Case Reports

Impact of nocturnal hemodialysis on peripheral uremic neuropathy

Sassan Ghazan-Shahi et al. BMC Nephrol. .

Abstract

Background: Uremic neuropathy is a common complication in patients with end stage kidney disease. Its pathogenesis has been attributed to accumulation of uremic toxins. Kidney transplantation has been the best therapeutic option.

Case presentation: We describe a case of severe uremic peripheral neuropathy, which improved after conversion from a conventional renal replacement therapy to nocturnal hemodialysis.

Conclusion: Enhanced uremic control by intensive hemodialysis may contribute at least in part to clinical and neurophysiological improvements of uremic neuropathy.

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Figures

Fig. 1
Fig. 1
Motor nerve conduction velocities. Before conversion to NHD, 1 year after conversion and 2 years after conversion
Fig. 2
Fig. 2
Sensory nerve conduction velocities. Before conversion to NHD, 1 year after conversion and 2 years after conversion. (R: Right)
See this image and copyright information in PMC

References

    1. Bolton CF, Baltzan MA, Baltzan RB. Effects of renal transplantation on uremic neuropathy. A clinical and electrophysiologic study. N Engl J Med. 1971;284:1170–1175. doi: 10.1056/NEJM197105272842102. - DOI - PubMed
    1. Bolton CF. Electrophysiologic changes in uremic neuropathy after successful renal transplantation. Neurology. 1976;26:152–161. doi: 10.1212/WNL.26.2.152. - DOI - PubMed
    1. Bolton CF. Peripheral neuropathies associated with chronic renal failure. Can J Neurol Sci. 1980;7:89–96. - PubMed
    1. Aggarwal HK, Sood S, Jain D, et al. Evaluation of spectrum of peripheral neuropathy in predialysis patients with chronic kidney disease. Ren Fail. 2013;35:1323. doi: 10.3109/0886022X.2013.828261. - DOI - PubMed
    1. Nielsen VK. The peripheral nerve function in chronic renal failure. V. Sensory and motor conduction velocity. Acta Med Scand. 1973;194:445–454. doi: 10.1111/j.0954-6820.1973.tb19470.x. - DOI - PubMed

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