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. 2015 Aug 12;10(8):e0134767.
doi: 10.1371/journal.pone.0134767. eCollection 2015.

Evaluation of Integrated Community Case Management in Eight Districts of Central Uganda

Denis Mubiru  1 , Robert Byabasheija  2 , John Baptist Bwanika  1 , Joslyn Edelstein Meier  1 , Godfrey Magumba  1 , Flavia Mpanga Kaggwa  2 , Jackson Ojera Abusu  2 , Alex Chono Opio  2 , Charles Clarke Lodda  2 , Jaanki Patel  3 , Theresa Diaz  4
Affiliations

Evaluation of Integrated Community Case Management in Eight Districts of Central Uganda

Denis Mubiru et al. PLoS One. .

Abstract

Objective: Evidence is limited on whether Integrated Community Case Management (iCCM) improves treatment coverage of the top causes of childhood mortality (acute respiratory illnesses (ARI), diarrhoea and malaria). The coverage impact of iCCM in Central Uganda was evaluated.

Methods: Between July 2010 and December 2012 a pre-post quasi-experimental study in eight districts with iCCM was conducted; 3 districts without iCCM served as controls. A two-stage household cluster survey at baseline (n = 1036 and 1042) and end line (n = 3890 and 3844) was done in the intervention and comparison groups respectively. Changes in treatment coverage and timeliness were assessed using difference in differences analysis (DID). Mortality impact was modelled using the Lives Saved Tool.

Findings: 5,586 Village Health Team members delivered 1,907,746 treatments to children under age five. Use of oral rehydration solution (ORS) and zinc treatment of diarrhoea increased in the intervention area, while there was a decrease in the comparison area (DID = 22.9, p = 0.001). Due to national stock-outs of amoxicillin, there was a decrease in antibiotic treatment for ARI in both areas; however, the decrease was significantly greater in the comparison area (DID = 5.18; p<0.001). There was a greater increase in Artemisinin Combination Therapy treatment for fever in the intervention areas than in the comparison area but this was not significant (DID = 1.57, p = 0.105). In the intervention area, timeliness of treatments for fever and ARI increased significantly higher in the intervention area than in the comparison area (DID = 2.12, p = 0.029 and 7.95, p<0.001, respectively). An estimated 106 lives were saved in the intervention area while 611 lives were lost in the comparison area.

Conclusion: iCCM significantly increased treatment coverage for diarrhoea and fever, mitigated the effect of national stock outs of amoxicillin on ARI treatment, improved timeliness of treatments for fever and ARI and saved lives.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Sources of treatment for children with fever, acute respiratory illness and diarrhoea in intervention area comparing baseline to end line, Uganda 2010–2012.
See this image and copyright information in PMC

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