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Comment
. 2015 Aug 14;290(33):20627.
doi: 10.1074/jbc.L115.669382.

Function and Structure of the RWD Domain

Marcelo Páez-Pereda  1 , Eduardo Arzt  2
Affiliations
Comment

Function and Structure of the RWD Domain

Marcelo Páez-Pereda et al. J Biol Chem. .
No abstract available

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Comment on

  • RWD Domain as an E2 (Ubc9)-Interaction Module.
    Alontaga AY, Ambaye ND, Li YJ, Vega R, Chen CH, Bzymek KP, Williams JC, Hu W, Chen Y. Alontaga AY, et al. J Biol Chem. 2015 Jul 3;290(27):16550-9. doi: 10.1074/jbc.M115.644047. Epub 2015 Apr 27. J Biol Chem. 2015. PMID: 25918163 Free PMC article.

References

    1. Alontaga A. Y., Ambaye N. D., Li Y. J., Vega R., Chen C. H., Bzymek K. P., Williams J. C., Hu W., Chen Y. (2015) RWD Domain as an E2 (Ubc9)-interaction module. J. Biol. Chem. 290, 16550–16559 - PMC - PubMed
    1. Carbia-Nagashima A., Gerez J., Perez-Castro C., Paez-Pereda M., Silberstein S., Stalla G. K., Holsboer F., Arzt E. (2007) RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia. Cell 131, 309–323 - PubMed
    1. Gerez J., Fuertes M., Tedesco L., Silberstein S., Sevlever G., Paez-Pereda M., Holsboer F., Turjanski A. G., Arzt E. (2013) In silico structural and functional characterization of the RSUME splice variants. PloS ONE 8, e57795. - PMC - PubMed
    1. Eddins M. J., Carlile C. M., Gomez K. M., Pickart C. M., Wolberger C. (2006) Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation. Nat. Struct. Mol. Biol. 13, 915–920 - PubMed
    1. Gerez J., Tedesco L., Bonfiglio J. J., Fuertes M., Barontini M., Silberstein S., Wu Y., Renner U., Paez-Pereda M., Holsboer F., Stalla G. K., Arzt E. (2014) RSUME inhibits VHL and regulates its tumor suppressor function. Oncogene 10.1038/onc.2014.407 - DOI - PubMed

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